Propranolol is a beta blocker drug. (Beta-blocker) used to treat high blood pressure. Chest pain, throbbing, arrhythmia. It is also used to treat conditions related to the heart and other circulatory systems. It is also used in the prevention and treatment of myocarditis. And is used to reduce the severity and frequency of migraine pain.
Its mechanism of action inhibits the action of certain chemicals in the body. Affecting or involving the heart and blood vessels It reduces the heart rhythm, blood pressure, and heart tension.
It is also used to treat red birthmark in young children (Infantile Hemangiomas) and may cause lesions or redness on the skin. Or it can lead to serious complications on the liver, brain, or digestive system. The drug is used as a liquid and is used for children aged 5 weeks and older.
Drug group beta blockers
Properties for high blood pressure and chest pain.
Pediatric and adult patient groups
Dosage forms, oral medication, intravenous drug
This drug should not be used if you have asthma. Have a slower-than-normal heart rhythm Or have a serious heart condition such as Sick Sinus Syndrome or Atrioventricular Block or AV Block
Oral liquid (Hemangeol) should not be used in young children weighing less than 2 kg.
A history of drug allergies and other allergic reactions should be reported to your doctor before using the drug. Because some ingredients in the drug may cause the patient to have an allergic reaction. Or has a dangerous response to beta blockers
Those planning to have children or are pregnant Always talk to your doctor before using propranolol.
Propranolol passes into breast milk and may harm breastfeeding. Therefore, let your doctor know before using the drug.
For the safety of using propranolol You should tell your doctor if you have any of the following conditions or symptoms.
Have muscle disorders
Having bronchitis (bronchitis), emphysema (Emphysema), asthma (bronchial asthma), or various breathing disorders
Have diabetes Or have low blood sugar
A slower-than-normal heart rhythm Or low blood pressure
Have heart failure or a heart failure (Congestive Heart Failure)
Have thyroid disorders
Have liver or kidney disease
A tumor on the adrenal gland Or Pheochromocytoma (Pheochromocytoma)
Have circulatory problems such as Raynaud’s Syndrome.
Adult: Intravenous, 1 mg, up to 10 mg for non-anesthesia patients, and 5 mg for anesthetized patient.
Adult: 60 mg orally per day and divided 3 times for 3 days in combination with alpha blocker.
For tumors that cannot be surgically removed, a daily dose of 30 mg is used.
Children: Take a dose of 0.25-0.5 mg / kg, 3-4 times a day.
High blood pressure (Hypertension)
Adult: oral tablet or solution, starting dose of 40-80 mg twice a day, normal dose 160-320 mg per day. Maximum of 640 mg per day. Long-acting capsule, starting dose 80 mg once a day, normal dose 120-160 mg per day. Maximum of 640 mg per day.
Children: Oral tablet: 1 mg / kg / day, 2 divided doses, 2-4 mg / kg per day, 2 divided doses, maximum 4 mg / kg per day, 2 to 3 divided doses.
Myocardial Infarction (Myocardial Infarction)
Adult: Oral tablet or solution of 40 mg, four times a day, used for 2-3 consecutive days, followed by 80 mg twice a day, alternative dosage of 180-240 mg per day, used for 5-21 days.
Hypertension in the hepatic vein system (Portal Hypertension)
Adults: oral tablet or solution, starting dose of 40 mg, twice daily, in weekly doses up to 160 mg, long acting capsule, 80 mg dose, and may be increased to 160 mg once daily, to a maximum of 320 mg per day.
Unilateral Headache (Prophylaxis of Migraine)
Adults: oral tablet or solution, starting dose of 40 mg, twice a day or 3 times a day, the usual dose of 120-240 mg per day Long-acting capsules of 80 mg per day May be increased to 160 mg per day Maximum of 240 mg per day
Children: Long-acting capsules or striped strands. For children younger than or equal to 12 years, the 10-20 mg dose is 2 or 3 times a day. For children 12 years of age, the initial dose is 40 mg 2 or 3 times a day, increasing weekly to 160 mg per day. Maximum of 240 mg per day
Arrhythmias (Cardiac Arrhythmias)
Adult: Take 30-160 mg per day. 3 divided meals per day
Children: Oral doses of 0.25-0.5 mg / kg 3-4 times a day.
Idiopathic tremor (Essential Tremor)
Adult: Take the primary dose of 40 mg 2 or 3 times a day, the normal dose is 120-240 mg per day.
Long-acting capsules of 80 mg per day May be increased to 160 milligrams once a day, up to a maximum of 240 milligrams per day.
Adults: Take a dose of 10-40 mg, 2 or 3 times a day, long-acting capsule, 80 mg once a day, up to 160 mg once a day.
Chest pain from ischemic heart (Angina Pectoris)
Adult: eat the basic size
40 mg twice a day, or 3 times a day, the normal dose is 120-240 mg per day. Maximum of 320 mg per day Long-acting capsules of 80 mg per day May be increased to 160 milligrams once a day, to a maximum of 240 milligrams per day.
Congenital heart disease in the lower left ventricle. (Hypertrophic Cardiomyopathy)
Adult: Take a dose of 10-40 mg 3-4 times a day.
Adults: Take a dose of 10-40 mg three to four times a day, 80 mg long-acting capsule per day. May be increased to 160 milligrams per day. Maximum of 240 mg per day
Children: Oral doses of 0.25-0.5 mg / kg 3-4 times a day.
- Dosage and duration of use are at the discretion of the treating physician.
Before using any medication, tell your doctor or pharmacist if you have a history of drug allergy, congenital disease, or are taking any medications at that time. Patients should read the label carefully before taking and use the drug strictly as directed by the physician. The dose should not be stopped, changed or adjusted by themselves.
This drug can be taken with or without food. But it should be at the same time each day. Long-acting capsules should not be crushed, chewed or removed. By swallowing the capsule whole
For oral medication (Hemangeol) administered to infants, the medication should be used during breastfeeding or after breastfeeding. The dosing dose should be spaced at least 9 hours and must be monitored if the baby is eating or feeding properly. And if the baby is found to have a change in body weight, you should notify the doctor. Because hemangeol dosing is based on the child’s body weight. If a child receiving Hemangeol is found to vomit. Or don’t want food Let the doctor know
Liquid drugs should be dosed with a syringe provided. Or a measuring spoon or a medicine cup And do not shake the liquid type drug
Patients should check their blood pressure regularly. And if necessary to undergo surgery You should tell your surgeon that you are using propranolol. Which patients may have to stop taking the drug for a while
You should tell your doctor you are taking propranolol before each medical exam. This is because medicines can cause abnormal results in some medical tests.
Patients taking propranolol for the treatment of hypertension. The drug should be continued even if symptoms have improved. Because hypertension often has no symptoms.
Taking propranolol is part of a treatment program. Which patients should control diet, exercise, weight control And maintain a healthy body while using drugs And see the doctor on a regular basis
Should be used strictly according to the doctor’s prescription. Do not skip or stop using the drug suddenly. Because stopping suddenly can worsen symptoms. In case of forgetting to take the medication at the specified time For short-acting propranolol To take the medicine immediately But if it’s close to taking the drug in the next 4 hours, skip to the next dose. For long-acting propranolol, take it immediately. But if it’s close to taking the drug in the next cycle at least 8 hours, skip to the next dose. Should not double the dose and if any unusual symptoms should see a doctor.
The drug should be stored at room temperature. Away from heat, humidity, sunlight and do not freeze the liquid medicine Hemangeol that has been used for 2 months (opened) should not be stored.
Side effects of Propranolol
The more common side effects of propranolol were nausea, vomiting, constipation, diarrhea, abdominal pain, decreased sex drive. Sexual dysfunction, insomnia, or fatigue
If a patient experiences allergic reactions to drugs, including hives, difficulty breathing, swelling of the face, lips, tongue or throat, they should contact a doctor immediately. Or have the following symptoms:
Slow or irregular heart rhythm
Feeling dizzy, as if to pass out
Has trouble breathing or wheezing
Swelling, weight gain
Sudden exhaustion Have vision problems Or lose the ability to coordinate body movements
Cold hands and feet
Depression, confusion, hallucinations
Have liver problems May cause symptoms such as nausea, upper abdominal pain, fatigue, loss of appetite, dark urine, pale stools, jaundice.
Low blood sugar It can lead to symptoms such as headache, hunger, fatigue, sweating, confusion, irritability, dizziness, rapid heartbeat. Feeling anxious
Low blood sugar in young children It can cause symptoms such as pale, purple or blue skin, sweating, crying, loss of appetite, chills, drowsiness, weakness, shallow breathing, seizures, loss of consciousness.
The reaction was violent on the skin. It can cause symptoms such as fever, sore throat, swelling of your face or tongue, burning eyes, sore skin, and a red or purple rash spread over your skin. And cause blisters